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Flagyl ER
Flagyl ER
Active Ingredient: Metronidazole
Flagyl ER is used for treating certain bacterial infections of the vagina (bacterial vaginosis).
Other names for this medication
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Flagyl ER 500mg
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INDICATIONS

Flagyl ER is used for treating certain bacterial infections of the vagina (bacterial vaginosis). Flagyl ER is an oral antiprotozoal and antibacterial. It is thought to work by entering the bacterial cell, acting on some components of the cell, and destroying the bacteria.

INSTRUCTIONS

Use Flagyl ER as directed by your doctor.

  • Take Flagyl ER by mouth on an empty stomach at least 1 hour before or 2 hours after eating.
  • Swallow Flagyl ER whole. Do not break, crush, or chew before swallowing.
  • To clear up your infection completely, take Flagyl ER for the full course of treatment. Keep taking it even if you feel better in a few days.
  • If you miss a dose of Flagyl ER, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses at once.

Ask your health care provider any questions you may have about how to use Flagyl ER.

STORAGE

Store Flagyl ER at 77 degrees F (25 degrees C). Brief storage at temperatures between 59 and 86 degrees F (15 and 30 degrees C) is permitted. Store away from heat, moisture, and light. Do not store in the bathroom. Keep Flagyl ER out of the reach of children and away from pets.

MORE INFO:

Active Ingredient: Metronidazole.

Do NOT use Flagyl ER if:

  • you are allergic to any ingredient in Flagyl ER or to another nitroimidazole (eg, tinidazole)
  • you are in the first trimestr of pregnancy
  • you are taking busulfan, an ergot alkaloid (eg, ergotamine), or you have taken disulfiram within the past 2 weeks
  • you are taking an HIV protease inhibitor that contains alcohol (eg, amprenavir solution); check with your pharmacist if you are unsure if the medicine contains alcohol
  • you drink alcohol.

Contact your doctor or health care provider right away if any of these apply to you.

Some medical conditions may interact with Flagyl ER. Tell your doctor or pharmacist if you have any medical conditions, especially if any of the following apply to you:

  • if you are pregnant, planning to become pregnant, or are breast-feeding
  • if you are taking any prescription or nonprescription medicine, herbal preparation, or dietary supplement
  • if you have allergies to medicines, foods, or other substances
  • if you have nerve, brain, or blood problems; Crohn disease; or a history of liver problems or seizures.

Some medicines may interact with Flagyl ER. Tell your health care provider if you are taking any other medicines, especially any of the following:

  • Disulfiram because side effects, such as mental or mood changes, may occur
  • Amiodarone because the risk of irregular heartbeat may be increased
  • Barbiturates (eg, phenobarbital) or phenytoin because they may decrease Flagyl ER's effectiveness
  • Anticoagulants (eg, warfarin), busulfan, cyclosporine, ergot alkaloids (eg, ergotamine), HIV protease inhibitors containing alcohol (eg, amprenavir solution ), lithium, or macrolide immunosuppressants (eg, tacrolimus) because the risk of their side effects may be increased by Flagyl ER.

This may not be a complete list of all interactions that may occur. Ask your health care provider if Flagyl ER may interact with other medicines that you take. Check with your health care provider before you start, stop, or change the dose of any medicine.

Important safety information:

  • Flagyl ER may cause dizziness. This effect may be worse if you take it with alcohol or certain medicines. Use Flagyl ER with caution. Do not drive or perform other possibly unsafe tasks until you know how you react to it.
  • Do not drink alcohol while you are taking Flagyl ER and for at least 3 days after the last dose.
  • Contact your doctor right away if stomach pain or cramps, severe diarrhea, or bloody stools occur. Do not treat diarrhea without first checking with your doctor.
  • Flagyl ER only works against bacteria; it does not treat viral infections (eg, the common cold).
  • Be sure to use Flagyl ER for the full course of treatment. If you do not, the medicine may not clear up your infection completely. The bacteria could also become less sensitive to this or other medicines. This could make the infection harder to treat in the future.
  • Long-term or repeated use of Flagyl ER may cause a second infection. Tell your doctor if signs of a second infection occur. Your medicine may need to be changed to treat this.
  • Flagyl ER may interfere with certain lab tests. Be sure your doctor and lab personnel know you are taking Flagyl ER.
  • Lab tests, including liver function and white blood cell counts, may be performed while you use Flagyl ER. These tests may be used to monitor your condition or check for side effects. Be sure to keep all doctor and lab appointments.
  • Use Flagyl ER with caution in the elderly; they may be more sensitive to its effects.
  • Flagyl ER should be used with extreme caution in children; safety and effectiveness in children have not been confirmed.
  • Pregnancy and breast-feeding: If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Flagyl ER while you are pregnant. Do not use Flagyl ER in the first 3 months of pregnancy. Flagyl ER is found in breast milk. Do not breastfeed while taking Flagyl ER.

All medicines may cause side effects, but many people have no, or minor, side effects.

Check with your doctor if any of these most common side effects persist or become bothersome:

Appetite loss; constipation; diarrhea; dizziness; headache; metallic taste; nausea; stomach upset; vomiting.

Seek medical attention right away if any of these severe side effects occur:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bloody stools; decreased coordination; increased or decreased urination; numbness, tingling, or burning of the arms, hands, legs, or feet; red, swollen, blistered, or peeling skin; seizures; severe diarrhea; severe or persistent dizziness or headache; sore throat, chills, or fever; speech problems; stiff neck; stomach pain or cramps; vaginal itching, odor, or discharge; vision loss or other vision changes; white patches in the mouth.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider.

Flagyl: A Medication That Treats Diarrhoea And Dysentery


About Flagyl: Flagyl contains the active ingredient Metronidazole. It is an antibacterial and anti-amoebic drug used in the treatment of amoebic dysentery. It also has good activity against anaerobic organisms and is used in circumstances where anaerobic infection is suspected to be likely or is proven. Flagyl is a first of this class of antibacterials originally developed from nitroimidazole which was introduced in 1959 for the treatment of Trichomoniasis. Flagyl was later found to be an effective amoebicide and this became its most widespread use. It also has broad spectrum activity against protozoa. Flagyl is selectively toxic to anaerobic microorganisms such as Bacteroides fragilis, Fusobacterium, clostridium perfringens, Cl. difficile, H. pylori, Campylobacter, peptococci and peptostreptococci. It facilitates the removal of the worm Dracunculus medinensis in Guinea worm infestation. Flagyl is not effective against aerobic bacteria.

How Flagyl Works: Flagyl (Metronidazole) is an antibacterial and antiamoebic agent, and is drug from the group of nitroimidazole compounds. It is selectively toxic to anaerobic organisms since it requires an anaerobic environment for proper functioning and its cidal action. After entering the cell via diffusion, the nitro group of Flagyl is reduced to nitro radical by certain redox proteins found only in anaerobic organisms. This nitro radical exerts its cytotoxic activity. This radical competes with the natural electron acceptors present the cell of the organism and prevents the functioning of the pyruvate ferredoxin oxidoreductase pathway. Flagyl thus prevents pyruvate oxidation and the energy metabolism of anaerobic organisms is disrupted. An aerobic environment does not allow Flagyl to be activated by the reductive mechanism. When an organism becomes resistant to Flagyl, it becomes deficient in the mechanism that is used to generate toxic nitro radicals from it.

How To Take Flagyl: Flagyl Online is used in the management of anaerobic infections as well as amoebic infestations, which can be localised or systemic. It is used in the treatment of Trichomoniasis, bacterial vaginosis, giardiasis, ulcerative stomatitis, as part of treatment for H. pylori induced gastritis and as part of regimens for preparation of bowel for surgery. Buy Flagyl Online is supplied as 800 mg and 400 mg tablets for oral consumption. An injectable form is also available and is used in the strengths of 500 mg/ 100 ml and 250 mg/ 100 ml. For the topical treatment of wounds and infections as well as intravaginal use, Flagyl creams and jelly preparations are available. The recommended dose for the management of dysentery of amoebic aetiology is 400-800 mg taken 3 times a day after meals. The duration of therapy is usually 5-7 days. In the management of systemic amoebiasis and liver infestations and abscesses, Buy Flagyl Online can be used in the injectable intravenous form at 500 mg 6 hourly till the patient can be resumed on tablet medication. In the treatment of Trichomoniasis, Buy Flagyl is administered as a single dose of 2 gm or as divided doses in a single day. Buy Flagyl is also the first line treatment of pseudomembranous colitis, and is given in double dose of 800 mg 3 times a day via oral route. When used for the treatment of other serious infections with anaerobic bacteria, Flagyl is given intravenously at 7.5 mg/kg at a 6 hourly interval.

Precautions And Side Effects Of Flagyl: Buy Flagyl can produce a Disulfiram like reaction and should be avoided in alcoholics for fear of dangerous adverse effects. It is not recommended for use in patients with blood dyscrasias and porphyria, those with neurological illness and in pregnancy in the 1st trimester. Dose reduction of Flagyl Online and use with caution is warranted in patients with hepatic dysfunction or renal impairment.
Flagyl can commonly cause effects like GI disturbances, bad taste, myalgias, headache, dizziness and rashes. Serious effects of Buy Flagyl Online include hepatic dysfunction, neuropathy and CNS effects like seizures.

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